Proper injection technique and site rotation are essential for GLP-1 medication effectiveness and minimizing skin problems. Here's a complete guide to injection best practices.
Why Rotation Matters
- Prevents lipodystrophy — Repeated injections in one spot cause tissue changes
- Ensures consistent absorption — Damaged tissue absorbs medication poorly
- Reduces injection site reactions — Gives skin time to recover
- Minimizes scarring — Distributes impact across larger area
Approved Injection Sites
Abdomen
Most popular site. Inject at least 2 inches from navel. Avoid waistband area. Offers consistent absorption.
Thigh
Front of thigh, about 4 inches above knee and 4 inches below hip. Easy to see and reach. Slightly slower absorption.
Upper Arm
Back of upper arm. May need assistance reaching. Good for those who prefer to hide injection sites.
Rotation Strategies
The Clock Method (Abdomen)
Imagine a clock around your navel. Start at 12 o'clock and move to a new "hour" position each week. After completing the circle, move further from center.
The Zone Method
Divide each injection area into zones. Use left side one week, right side the next. Or alternate between abdomen, left thigh, right thigh weekly.
Distance Rule
Always inject at least 1 inch (2.5 cm) from your previous injection site. This ensures adequate tissue recovery between uses.
Injection Technique
Step 1: Prepare
Wash hands thoroughly. Allow refrigerated medication to reach room temperature (10-15 min). Check expiration date and that liquid is clear.
Step 2: Clean Site
Clean the injection site with alcohol swab. Let it dry completely before injecting.
Step 3: Inject
Pinch skin if needed (depending on body composition). Insert needle at 90-degree angle. Press button and hold for 10 seconds after the click.
Step 4: After Care
Remove needle straight out. Don't rub the site. Light pressure with cotton ball if bleeding. Document site used.
Sites to Avoid
- Within 2 inches of the navel
- Areas with scars, bruises, or skin problems
- Hardened or lumpy areas (signs of lipodystrophy)
- Red, swollen, or tender skin
- Stretch marks or moles
Tracking Your Injections
Keep a simple log to ensure proper rotation:
- Use a journal or app to record date and site
- Take photos to track site appearance over time
- Note any reactions or issues at specific sites
- Set reminders to check injection sites regularly
Official Summary
Consistent site rotation is a simple habit that prevents problems down the road. Choose a rotation system that works for you and stick with it. If you notice any skin changes, lumps, or persistent reactions, consult your healthcare provider.